Around the middle of the 17th century with the advent of the scientific method, a period of great change begins, called the scientific revolution. Many great scientists, with their theories and ideas, change our perception of the universe: Galileo Galilei, Copernicus, Kepler, Bacon and, above all, Sir Isaac Newton.

In Newton, players take the role of a young scientist who wants to become one of the great geniuses of this period. To do this, they travel around Europe, visit universities and cities, study to discover new theories, build new tools, and work to earn money.